Palmar hyperhidrosis is defined as excessive sweating of the hands, causing real daily relationship issues for those who suffer from it. A handshake is literally the first contact to begin a friendly or social relationship. Sweaty hands immediately taint it. To stop hand perspiration, aesthetic medicine has an effective solution with what could be called a Botox anti-perspiration injection.
The causes: where does palmar hyperhidrosis come from?
It is a significant sweating of the palms of the hands, resulting from an increase in sweat secretion by the sweat glands located on the palmar surface of the hands.
How do the sweat glands work?
Sweat has a role in thermal (heat elimination) and excretory (toxin elimination) regulation. There are approximately 4 million sweat glands distributed throughout our body, divided into two categories:
- The apocrine glands attached to the hairs. They are located in the armpits and lower abdomen, near the sexual organs. Their rather thick sweat is fragrant (sui generis odor), with urea, ammonia and pheromones.
- The eccrine glands are the most abundant, they are the ones found on the hands. Their liquid and odourless sweat consists mainly of water, mineral salts and lactic acid.
The production of sweat is controlled by the sympathetic autonomic nervous system (ANS), which also releases adrenaline during stress. However, for the sweat glands and the hair arrector muscle, the terminal neurotransmitter is acetyl choline, which triggers the secretion of sweat.
How does palmar hyperhidrosis appear?
Hyperhidrosis affects up to 25% of the population in a variable manner, with increased secretion of sweat in certain areas of the body.
It is called a primitive or primary hyperhidrosis if it is unexplained (idiopathic cause), with up to 3 liters of sweat per day, compared to at most one liter in a healthy adult. Stress increases this sweat secretion since it is regulated by the release of adrenaline.
It is a secondary hyperhidrosis when a specific cause is identified, such as menopause, thyroid disease, neurological disorders, diabetes..
Excessive sweating of the hands is a primary hyperhidrosis, localized to the palms.
Symptoms: how does palmar hyperhidrosis manifest itself?
It is an abnormal production of sweat and usually odourless.
The main sign is therefore this abnormal sweating of the hands, expressed in the form of clammy hands. It rarely leads to skin complications, sometimes with some redness in hot weather.
It mainly causes social problems, because sweating reflects the image of a neglected, worried or sick person.
Hyperhidrosis of the hands can quickly give discomfort or anxieties in socio-professional life, especially as it induces a vicious circle: we stress because we sweat, so we sweat even more.
This can lead to a form of social and then psychological isolation. Anyone suffering from hand sweating must therefore seek treatment.
Solutions to permanently stop hand sweating
The secretion of sweat obeys two "opposite" neuro-mediators: adrenaline as the starting point, and acetylcholine as the end point.
Botulinum toxin acts on the terminal phase as an antiperspirant Botox injection: in fact, botulinum toxin blocks acetylcholine. In the absence of a signal, the sweat glands stop their own secretion.
The antiperspirant action is local, at the injection site, reversible (the botulinum toxin inhibits the neurotransmitter for 6 months): it eliminates sweaty hands. The result can be seen after 5 to 10 days after the injection, and this anti-perspiration treatment of the hands must be repeated about twice a year.
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